Autophagy and Human Cancers
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Autophagy".
Deadline for manuscript submissions: closed (25 September 2023) | Viewed by 19203
Special Issue Editors
Interests: characterization of multidrug-resistant tumor cells; in vitro study of apoptosis induced by chemotherapeutic drugs; in vitro study of autophagy (cell survival mechanism or type II programmed cell death); in vitro study of new anticancer strategies based on the use of natural products in combination with drugs, on electrochemotherapy, and on liposomes; study of interaction between cells and metal nanoparticles (ZnO or Ag-NPs) to investigate nanotoxicology
Special Issues, Collections and Topics in MDPI journals
Interests: ultrastructural pathology; nanomedicine; nanotoxicology; cell biology; anticancer therapy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Autophagy is a conserved catabolic process, essential for the maintenance of cellular homeostasis. In cancer, autophagy is related to the cell type, the different tumor, the microenvironment and the stage of the disease. During tumor development, autophagy is able to disfavor malignant transformation, limiting the production of reactive oxygen species and DNA damage. In advanced stages of the disease, autophagy evolves to support cancer progression through the regulation of the immune response or the secretion of cytokines and growth factors. Furthermore, autophagy can be involved in mechanisms of resistance to anticancer therapy. In this Special Issue, we will try to improve the understanding of autophagy mechanisms, especially those involved in the growth and aggressiveness of the tumor and the regulation of resistance to chemotherapy.
Dr. Maria Condello
Prof. Dr. Stefania Meschini
Guest Editors
Manuscript Submission Information
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Keywords
- autophagy
- cell death
- cancer
- resistance mechanisms
- microenvironment