Recent Studies on Biological Activities of Alkaloids and Their Modifications

Dear Colleagues,

In the search for new biologically active compounds, particular attention is paid to natural products isolated from plants. These include secondary metabolites with defense or signaling functions or as symbiotic agents between organisms or plants. Among these are alkaloids, which, due to their chemical diversity and potential therapeutic properties, are used as model compounds or precursors in the synthesis of modern drugs. These compounds exhibit various physiological effects, some of which are used in pharmacology, such as codeine, brucine, morphine, ephedrine, and quinine. Based on alkaloid biosynthetic precursors and heterocyclic ring systems, they have been classified into different categories, such as indole and purine alkaloids, essential therapeutic molecules. This Special Issue aims to collect publications on the impact of alkaloid modifications on changes in their broadly understood biological activity. We invite authors who deal not only with the design and synthesis of alkaloid derivatives, but also with their bioactivity and mechanism of action. These can be both research papers and reviews.

Dr. Beata Jasiewicz
Guest Editor

Manuscript Submission Information

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• alkaloids
• chemical modification
• biological activity