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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Anti-cancer Effects of Natural Products
edited by
submission deadline 25 Jun 2024 | 3 articles | Viewed by 5068 | Submission Open
Keywords: cancer; natural products; herbal medicine; anticancer therapies; metastasis; recurrence; resistance mechanism; novel biomarker
(This special issue belongs to the Section Molecular Pharmacology)
Development, Characterization and Applications of Novel Polymeric Materials and Composites submission deadline 25 Jun 2024 | 5 articles | Viewed by 4427 | Submission Open
Keywords: diagnosis; therapy; polymers; composite materials; theoretical model
(This special issue belongs to the Section Macromolecules)
Liver Diseases: From Molecular Basis to Potential Therapy
edited by
submission deadline 25 Jun 2024 | 3 articles | Viewed by 3787 | Submission Open
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
MicroRNAs in Cancer Therapy 2.0
edited by
submission deadline 25 Jun 2024 | 3 articles | Viewed by 3696 | Submission Open
Keywords: miRNA; cancer; apoptosis; proliferation; metastasis; resistance; chemotherapy; natural product; herbal medicine; plant extract; side effects of chemotherapy
(This special issue belongs to the Section Molecular Oncology)
Advances in Genetics and Phylogenomics of Tree
edited by
submission deadline 25 Jun 2024 | 4 articles | Viewed by 3110 | Submission Open
Keywords: genomics; gene expression; gene family; DNA methylation; phylogenomic; genome-wide association studies (GWASs)
(This special issue belongs to the Section Molecular Plant Sciences)
New Molecular Mechanisms and Markers in Inflammatory Disorders, 2nd Edition submission deadline 25 Jun 2024 | 2 articles | Viewed by 2622 | Submission Open
Keywords: inflammation; inflammatory disorders; biomarkers; molecular mechanism of inflammation; molecular signaling
(This special issue belongs to the Section Molecular Immunology)
New Molecular Progression of Stem Cell Therapy for Neurological Disorders
edited by
submission deadline 25 Jun 2024 | 2 articles | Viewed by 2376 | Submission Open
(This special issue belongs to the Section Molecular Neurobiology)
The Role of Glutathione Metabolism in Health and Disease submission deadline 25 Jun 2024 | 2 articles | Viewed by 2334 | Submission Open
Keywords: glutathione metabolism; glutathione activity; cancer; reactive oxygen species (ROS)
(This special issue belongs to the Section Biochemistry)
The Role of Mineralocorticoid Receptors in Human Diseases
edited by Roberto Palacios-Ramirez
submission deadline 25 Jun 2024 | 1 articles | Viewed by 1921 | Submission Open
Keywords: mineralocorticoid receptor; fibrosis; inflammation
(This special issue belongs to the Section Molecular Biology)
Harnessing Nature’s Potential: Plant-Derived Substances for Controlling Appetite and Promoting Weight Management
edited by and Ettore Novellino
submission deadline 25 Jun 2024 | 1 articles | Viewed by 1816 | Submission Open
Keywords: plant-derived substances; obesity; satiety control; weight management; gut hormones; bioactive compounds; energy metabolism; phytochemicals; molecular mechanisms; clinical trials
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Heterogeneous Catalysts: Design, Synthesis, and Applications
edited by
submission deadline 25 Jun 2024 | 1 articles | Viewed by 1711 | Submission Open
Keywords: nanoparticles; metal nanoparticles; metal active sites; single-site catalysts; structure– activity relations; heterogeneous catalysis; nanoparticle synthesis; in situ characterization; selectivity; molecular catalysis
(This special issue belongs to the Section Materials Science)
Mass Spectrometry Imaging for Drug Pharmacokinetics and Drug Delivery System
edited by
submission deadline 25 Jun 2024 | 1 articles | Viewed by 1605 | Submission Open
Keywords: Mass Spectrometry Imaging; drug pharmacokinetics; drug delivery systems; method development
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Pathogenesis of Intervertebral Disc Disease
edited by
submission deadline 25 Jun 2024 | 1 articles | Viewed by 1559 | Submission Open
Keywords: stem cells; cytokines; degenerative disc disease; disc degeneration; disc herniation; exosomes; genetics; genome engineering; inflammation; ion channels
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Effects of Environmental Contaminants on Cell Signaling Pathways
edited by Brad L. Upham
submission deadline 25 Jun 2024 | 1 articles | Viewed by 1208 | Submission Open
Keywords: cell signaling; environmental contaminants; signal transduction; gap junction; toxic mechanisms
(This special issue belongs to the Section Molecular Biology)
Molecular Mechanisms of C-reactive Protein
edited by Mark Slevin
submission deadline 25 Jun 2024 | 1 articles | Viewed by 1094 | Submission Open
Keywords: C-reactive protein; cell signalling; inflammation; pathological processes
(This special issue belongs to the Section Molecular Biology)
Molecular Insights into Muscular Dystrophy
edited by
submission deadline 25 Jun 2024 | 1 articles | Viewed by 1012 | Submission Open
Keywords: zebrafish; muscular dystrophy; signalling pathways; disease pathogenesis; drug screening; mitochondria; metabolism; mitochondrial respiration; oxidative stress; cell apoptosis; muscle differentiation; satellite cells
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Elucidating Disease Mechanisms and Designing Therapeutics Using Computer-Aided Simulations and Modeling
edited by
submission deadline 25 Jun 2024 | 1 articles | Viewed by 986 | Submission Open
Keywords: X-ray diffraction; electron scanning microscopy; protein crystallization; protein structure; drug design approaches; G-protein-coupled receptors; G-protein signaling; enzyme kinetics; ligand docking; lead optimization; machine learning; quantum computing
(This special issue belongs to the Section Molecular Informatics)
New Molecular Insights into the Gut Microbiome
edited by Hyunju You
submission deadline 25 Jun 2024 | 1 articles | Viewed by 922 | Submission Open
Keywords: microbiome; gut microbiota; nutraceuticals; immuno-metabolic diseases
(This special issue belongs to the Section Molecular Microbiology)
New Insight into Extracellular Vesicles in Proliferative Diseases
edited by Sergio Esquivel-Ruiz
submission deadline 25 Jun 2024 | 1 articles | Viewed by 747 | Submission Open
Keywords: proliferation; extracellular vesicles; intercellular communication; vesicle cargo; therapeutic applications; biomarkers
(This special issue belongs to the Section Molecular Immunology)
Effect of Diet on Human Neurocognitive Function
edited by
submission deadline 25 Jun 2024 | Viewed by 285 | Submission Open
Keywords: cognition; cognitive impairment; dietary pattern; nutrients; nervous cells
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Insights into Metabolic Pathways and Age-Related Pathologies
edited by and Monia Cecati
submission deadline 25 Jun 2024 | Viewed by 263 | Submission Open
Keywords: aging; age-associated diseases; dysregulated metabolic pathways; inflammation; biomarkers; therapeutics
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Endocrine Modulation of Immune Function
edited by Juan Pablo Mackern-Oberti
submission deadline 25 Jun 2024 | Viewed by 202 | Submission Open
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Molecular Basis and Therapies in Neurological Disorders
edited by Mihaela-Adela Vinţan
submission deadline 25 Jun 2024 | Viewed by 158 | Submission Open
Keywords: neurological diseases; nerve damage; Alzheimer's disease; Parkinson’ s; stroke; pathogenesis; drug treatment; nanomedicine delivery; gene therapy; stem cell therapy; therapeutic targets; nerve regeneration; molecular markers; gene editing technology
(This special issue belongs to the Section Molecular Neurobiology)
Optical Molecular Systems: From Design to Applications submission deadline 25 Jun 2024 | Viewed by 147 | Submission Open
Keywords: luminescent materials; spectral conversion; smart optical materials; human-centric lighting; healthcare diagnostics; imaging; and therapeutics; advanced optical sensors
(This special issue belongs to the Section Materials Science)
Electronic and Steric Effects of Catalysts on Polymerization Mechanisms
edited by Lucia Caporaso and
submission deadline 25 Jun 2024 | Viewed by 99 | Submission Open
Keywords: homogeneous catalysis; stereospecific polymerization; polymer synthesis; polymer characterization
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Functional Nanomaterial: Design, Synthesis and Applications submission deadline 27 Jun 2024 | 4 articles | Viewed by 4080 | Submission Open
Keywords: functional organic nanomaterials; design; synthesis; applications; drug delivery; biosensors; catalysis; energy conversion
(This special issue belongs to the Section Molecular Nanoscience)
Advanced Research on the Adrenal Gland and Hormones
edited by Marcin Ruciński
submission deadline 27 Jun 2024 | Viewed by 205 | Submission Open
Keywords: bioactive peptides; adrenal gland; adrenocortical carcinoma; HPA axis; G protein-coupled receptor; hormones; steroidogenesis
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Mechanisms of Bioactive Nutrients Promoting Health through Gut Microbiota 2.0
edited by and
submission deadline 28 Jun 2024 | 8 articles | Viewed by 38748 | Submission Open
Keywords: phytochemicals; complex carbohydrates; bioactive nutrients; gut microbiota; prebiotics; probiotics; inflammation; molecular mechanisms; human health
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Research in Prebiotics, Probiotics and Postbiotics
edited by and Haruki Kitazawa
submission deadline 28 Jun 2024 | 7 articles | Viewed by 8894 | Submission Open
Keywords: probiotics; prebiotics; postbiotics; symbiotics; immunobiotics; functional foods; health improvement; mucosal immunology; microbiota
(This special issue belongs to the Section Molecular Microbiology)
Natural Bioactive Compounds for Human Health 2.0
edited by and
submission deadline 28 Jun 2024 | 6 articles | Viewed by 8429 | Submission Open
Keywords: natural bioactive plant products; biological and pharmacological activity; natural plant drug discovery and development; nutraceuticals; botanical dietary supplement
(This special issue belongs to the Section Molecular Pharmacology)
Nonalcoholic Fatty Liver Disease/Metabolic Associated Fatty Liver Disease: New Insights 3.0 submission deadline 28 Jun 2024 | 5 articles | Viewed by 7954 | Submission Open
Keywords: nonalcoholic fatty liver disease (NAFLD); metabolic associated fatty liver disease (MAFLD); nonalcoholic steatohepatitis (NASH); fatty liver; cardiovascular disease
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Genetics- and Genomics-Based Crop Improvement and Breeding 2.0
edited by Jian Ma
submission deadline 28 Jun 2024 | 8 articles | Viewed by 6881 | Submission Open
Keywords: crop; germplasm; genetics; genomics; breeding
(This special issue belongs to the Section Molecular Plant Sciences)
Characterization of Extracellular Vesicles in Disease
edited by
submission deadline 28 Jun 2024 | 3 articles | Viewed by 6250 | Submission Open
Keywords: extracellular vesicle; exosomes; microvesicles; vesicle cargo
(This special issue belongs to the Section Molecular Biology)
Molecular and Structural Research Advances in Model Plants submission deadline 28 Jun 2024 | 5 articles | Viewed by 5578 | Submission Open
Keywords: A. thaliana; plant biology; model organisms; plant models; non-model plant models
(This special issue belongs to the Section Molecular Plant Sciences)
Plant Resilience Mechanisms for Coping with Environmental Stresses: Paving the Path to a Sustainable Future
edited by
submission deadline 28 Jun 2024 | 3 articles | Viewed by 4062 | Submission Open
Keywords: antioxidants; drought tolerance; growth patterns; morphological adaptations; physiological changes; pathogen defense; protective proteins; root system development; stomatal closure; stress signaling pathways
(This special issue belongs to the Section Molecular Plant Sciences)
Cytokines: From Cancer to Autoimmunity 2.0 submission deadline 28 Jun 2024 | 2 articles | Viewed by 3179 | Submission Open
Keywords: cytokines; cancer; autoimmunity; inflammation; gene expression regulation
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Molecular and Translational Medicine 2.0 submission deadline 28 Jun 2024 | 3 articles | Viewed by 2754 | Submission Open
Keywords: molecular pathology; biomarkers; signature transduction; cell signaling; molecular mechanisms; translational research; pathophysiology
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Notch Signaling in Health and Disease 2.0 submission deadline 28 Jun 2024 | 3 articles | Viewed by 2558 | Submission Open
Keywords: dermatological diseases; Notch signaling; keratinocytes; inflammation; autoinflammation; differentiation; keratinization; proliferation
(This special issue belongs to the Section Biochemistry)
Molecular Research of Hepatocellular Carcinoma
edited by
submission deadline 28 Jun 2024 | 2 articles | Viewed by 2556 | Submission Open
Keywords: hepatocellular carcinoma; liver inflammation; signaling pathways; novel markers; genetic factors; target therapies
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Current Research for Castration Resistance Prostate Cancer
edited by
submission deadline 28 Jun 2024 | 1 articles | Viewed by 2395 | Submission Open
Keywords: prostate cancer; castration-resistant prostate cancer; therapy resistance; biomarkers; androgen receptor; new therapies; tumor microenvironment
(This special issue belongs to the Section Molecular Oncology)
Molecular Mechanism in Multiple Sclerosis and Related Disorders 2.0
edited by , and Kazuo Fujihara
submission deadline 28 Jun 2024 | 2 articles | Viewed by 2391 | Submission Open
Keywords: neurodegeneration; multiple sclerosis; NMOSD; MOGAD; disease modifying treatments
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Protective Immune Response to Virus Infection and Vaccines
edited by Zhifang Zhang
submission deadline 28 Jun 2024 | 2 articles | Viewed by 2020 | Submission Open
Keywords: pathogenic virus; zoonotic virus; vaccine; immune response; virus– host interaction
(This special issue belongs to the Section Molecular Immunology)
Mucopolysaccharidoses: Diagnosis, Treatment and Management 4.0
edited by , and Roberto Giugliani
submission deadline 28 Jun 2024 | 1 articles | Viewed by 1981 | Submission Open
Keywords: mucopolysaccharidoses; glycosaminoglycans; proteoglycans; lysosomal dysfunction; cell function; metabolic disease
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Magnetic Nanoparticles for Biomedical and Imaging Applications 2.0 submission deadline 28 Jun 2024 | 2 articles | Viewed by 1907 | Submission Open
Keywords: magnetic nanoparticles and targeted drug delivery; magnetic nanoparticles as instruments for nanotopography; magnetic nanoparticles for bioimaging; magnetic nanoparticles for cell and biomolecule separation; magnetic nanoparticles and non-invasive imaging; magnetic nanoparticles and nanocomposites
(This special issue belongs to the Section Molecular Nanoscience)
The Role of Natural Products in Non-alcoholic Fatty Liver Disease submission deadline 28 Jun 2024 | 1 articles | Viewed by 1628 | Submission Open
Keywords: fatty liver; steatosis; steatohepatitis; hepatocarcinoma; non-alcoholic fatty liver disease; inflammation; fibrosis; oxidative stress; liver injury; active biomolecules; natural products; food; precision nutrition
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Advanced Research on Macrophages in Human Health and Disease submission deadline 28 Jun 2024 | 1 articles | Viewed by 1564 | Submission Open
Keywords: macrophages; phenotype; plasticity; inflammation; molecular mechanisms; signaling pathways; human disease; immunopathology; immunotherapy; target identification; natural compounds; drugs
(This special issue belongs to the Section Molecular Immunology)
Developing Methods and Molecular Basis in Plant Biotechnology submission deadline 28 Jun 2024 | 1 articles | Viewed by 1455 | Submission Open
Keywords: plant biotechnology; plant genetics; plant proteomics; plant metabolomics; stress
(This special issue belongs to the Section Molecular Plant Sciences)
Beyond Antioxidants and Analgesics: From Natural Compounds to Synthetic Derivatives submission deadline 28 Jun 2024 | 1 articles | Viewed by 916 | Submission Open
Keywords: pain; oxidative stress; inflammation; bioactive compounds; antioxidant
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Mechanisms and Therapeutic Targets in Skin Diseases
edited by Hanna Mys̈liwiec
submission deadline 28 Jun 2024 | 1 articles | Viewed by 744 | Submission Open
Keywords: inflammatory skin diseases; systemic inflammation; infectious skin diseases; comorbidity; pathogenesis; cytokines
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Drug Design and Development for Neurological Diseases submission deadline 28 Jun 2024 | 1 articles | Viewed by 699 | Submission Open
Keywords: neurological disorders and their therapies; molecular modeling; synthesis and structural analysis; neurotransmitters ligands; mechanism of action; drug repurposing
(This special issue belongs to the Section Molecular Pharmacology)
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