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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Redox Physiology in Biomedicine and Ecophysiology: The Influence of Various Substances on the Redox Regulation of Cell Metabolism, 2nd Edition
edited by
submission deadline 30 May 2024 | 1 articles | Viewed by 992 | Submission Open
Keywords: redox-signalling pathways; antioxidative and hypoglicemic effects of plant extracts; prooxidant/antioxidant status in the cells; redox active trace metals; reproductive health of women and men: infertility/sterility; xenobiotics in aquatic organims; essential trace elements and immunological parameters in COVID/post-COVID patients
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Molecular Research on Cardiac Regenerative Medicine
edited by Ken Takahashi
submission deadline 30 May 2024 | 1 articles | Viewed by 973 | Submission Open
Keywords: heart failure; human induced pluripotent stem cells; hiPSCs; 3D bioprinting; regenerative medicine; tissue engineering
(This special issue belongs to the Section Molecular Biology)
Molecular Research on Prostate Cancer
edited by
submission deadline 30 May 2024 | 1 articles | Viewed by 969 | Submission Open
Keywords: prostate cancer; molecular biology; genomics; biomarkers; signaling pathways; precision medicine; treatment resistance; epigenetics; therapeutic targets
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Research in Viral Hepatitis and Liver Cancer
edited by
submission deadline 30 May 2024 | 1 articles | Viewed by 968 | Submission Open
Keywords: hepatitis B; hepatitis C; hepatitis D; hepatocellular carcinoma
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The 150th Anniversary of the Discovery of L.A. Ranvier: Specialization and Plasticity of Fiber Types in the Vertebrate Skeletal Muscles submission deadline 30 May 2024 | 1 articles | Viewed by 940 | Submission Open
(This special issue belongs to the Section Molecular Biology)
Research on Molecular Dynamics 2.0
edited by and
submission deadline 30 May 2024 | 1 articles | Viewed by 897 | Submission Open
Keywords: molecular dynamics; quantum mechanics/molecular mechanics approaches; conformational change; dynamic changes of intermolecular interactions; protein– ligand interactions; nucleic acid ligand interactions; computational modeling of molecular systems; drug design and delivery; structure– function relationships in proteins; simulation of drug-like molecules and lipid membranes
(This special issue belongs to the Section Molecular Biophysics)
Molecular Research in Chemical Mixtures Toxicology
edited by
submission deadline 30 May 2024 | 1 articles | Viewed by 881 | Submission Open
Keywords: mixtures toxicity; pulmonary toxicity; inhalation lung; screening; biocide; emulsifier; household products; spray
(This special issue belongs to the Section Molecular Toxicology)
Cellular and Molecular Studies of Dopamine and Its Receptors
edited by
submission deadline 30 May 2024 | 1 articles | Viewed by 774 | Submission Open
Keywords: neuroscience; dopamine; dopamine receptors; peripheral immunity
(This special issue belongs to the Section Molecular Biology)
Exploring Signaling, Cellular and Molecular Plant Defense against Viruses submission deadline 30 May 2024 | 1 articles | Viewed by 728 | Submission Open
Keywords: plant viruses; cellular and molecular host response; resistance; plant– virus interaction; innate immunity; microscopy; plant defense systems; signal transduction
(This special issue belongs to the Section Molecular Plant Sciences)
Plasticity of the Nervous System after Injury 2.0 submission deadline 30 May 2024 | 1 articles | Viewed by 704 | Submission Open
Keywords: neural plasticity; axonal regeneration; nerve injury; glial cells; central nervous system
(This special issue belongs to the Section Molecular Neurobiology)
Natural-Sourced Compounds: Chemical Composition, Biological Activity and Toxicity Assessment
edited by and Faouzi Errachidi
submission deadline 30 May 2024 | Viewed by 699 | Submission Open
Keywords: natural-sourced compounds; marine resources; chemical composition; biological activity; antimicrobial; antioxidant; green extraction methods; toxicity assessment
(This special issue belongs to the Section Molecular Toxicology)
Recent Studies on Biological Activities of Alkaloids and Their Modifications
edited by
submission deadline 30 May 2024 | 1 articles | Viewed by 679 | Submission Open
Keywords: alkaloids; chemical modification; biological activity
(This special issue belongs to the Section Biochemistry)
Advances on Retinal Diseases 2.0
edited by Minzhong Yu
submission deadline 30 May 2024 | Viewed by 669 | Submission Open
Keywords: retina; optic nerve; ocular disorder; retinal disease; genetic mutation; aging; drug side effects; novel mutations/biomarkers; signaling pathways; spectral domain optical coherence tomography; stem cell; gene therapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Hepatitis Viruses and Hepatocellular Carcinoma: Research, Treatment and Challenges
edited by
submission deadline 30 May 2024 | Viewed by 643 | Submission Open
Keywords: HBV; HDV; HCV; virus replication and pathogenesis; antivirals; virus– cell interaction; vaccine development; hepatocellular carcinoma
(This special issue belongs to the Section Molecular Immunology)
Health, Disease, and Chronobiology: Molecular and Genetics Aspects submission deadline 30 May 2024 | Viewed by 632 | Submission Open
Keywords: chronobiology; timing of food; sleep; time-restricted eating; metabolism; genomics; epigenomics; metabolomics; microbiome; mechanisms
(This special issue belongs to the Section Molecular Biology)
Molecular Docking, Interaction and Mechanism of Action of Bioactive Peptides
edited by
submission deadline 30 May 2024 | 1 articles | Viewed by 614 | Submission Open
Keywords: bioactive peptides; molecular docking; molecular dynamics simulations; computer-aided screening; structure– activity relationship; bioavailability; bioinformatics
(This special issue belongs to the Section Molecular Informatics)
Nanotechnology in the Treatment and Diagnosis of Cancer: Opportunities and Challenges
edited by Lucyna Kapka-Skrzypczak
submission deadline 30 May 2024 | 1 articles | Viewed by 533 | Submission Open
Keywords: nanomaterials; cancer; nanomedicine; biological effects; cancer therapy; metastasis
(This special issue belongs to the Section Molecular Nanoscience)
Molecular Mechanism and Treatment of Allergic Asthma
edited by and Marcello Cottini
submission deadline 30 May 2024 | 1 articles | Viewed by 507 | Submission Open
Keywords: allergic asthma; epithelial barrier damage; protease allergen; type 2 inflammation
(This special issue belongs to the Section Molecular Immunology)
Advances in Electrochemistry of Metal Nanomaterials
edited by Evangelina Pensa, Miriam C. Rodríguez González and Maria Pilar Carro Reglero
submission deadline 30 May 2024 | Viewed by 507 | Submission Open
Keywords: metal nanomaterials; electrochemistry; electrocatalysis; charge storage capabilities; electron transfer kinetics
(This special issue belongs to the Section Molecular Nanoscience)
Drought Stress Tolerance in Plants in 2024
edited by
submission deadline 30 May 2024 | 1 articles | Viewed by 487 | Submission Open
Keywords: root physiology; drought tolerance; photosynthesis; water deficit stress; shoot– root interaction; salinity; crop plants
(This special issue belongs to the Section Molecular Plant Sciences)
Pathogenetic Factors of Ophthalmological Symptoms in Systemic Diseases submission deadline 30 May 2024 | 1 articles | Viewed by 445 | Submission Open
Keywords: diagnosis; uveitis; keratitis; ocular inflammation; hypersensitivity
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Crosstalk between Lipids and Immunity
edited by
submission deadline 30 May 2024 | Viewed by 405 | Submission Open
Keywords: eicosanoids; sphingolipids; endocannabionoids; specialized pro-resolving mediators; lysophospholipids; lipidomics; membrane-lipids therapy
(This special issue belongs to the Section Molecular Immunology)
New Molecular Insights into Antimicrobial Photo-Treatments
edited by Pietro Delcanale
submission deadline 30 May 2024 | 1 articles | Viewed by 396 | Submission Open
Keywords: photodynamic inactivation; photo-thermal therapy; photosensitization; antimicrobials; reactive oxygen species; photo-treatments; antibiotic resistance; singlet oxygen; antivirals
(This special issue belongs to the Section Molecular Microbiology)
Molecular Insight into Dentistry and Craniofacial Surgery: Celebrating the 110th Anniversary of Dentistry in Italy
edited by
submission deadline 30 May 2024 | Viewed by 378 | Submission Open
Keywords: dentistry; craniofacial district; technological; oral health; molecular research; materials; restorative dentistry; prosthodontics; oral surgery; implantology; pediatric dentistry; orthodontics; temporomandibular disorder
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Zinc Enzymes for Drug Design and Drug Development submission deadline 30 May 2024 | Viewed by 333 | Submission Open
Keywords: zinc enzymes; carbonic anhydrases; matrix metalloproteinases; histone deacetylases; zinc metalloenzymes; drug design
(This special issue belongs to the Section Molecular Pharmacology)
Nanocomposites Based on Graphite and Its Derivatives for Cutting-Edge Applications submission deadline 30 May 2024 | Viewed by 329 | Submission Open
Keywords: nanostructures; graphene nanocomposites; sustainable procedures; electrodes; thin films; sensors; photocatalysis; energy conversion; energy storage
(This special issue belongs to the Section Molecular Nanoscience)
Nutrient Sensing in Human Metabolic Diseases: Associated Molecular Mechanisms submission deadline 30 May 2024 | Viewed by 324 | Submission Open
Keywords: nutrition; functional food; bioactive compounds; gene; nutrigenomics; nutrigenetics; metabolomics; proteomics; microbiota; chronic diseases
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Immune Modulation of Macrophages 2.0
edited by and Yan Chen
submission deadline 30 May 2024 | Viewed by 316 | Submission Open
Keywords: macrophages; treatment; phenotype change; pathway analysis
(This special issue belongs to the Section Molecular Immunology)
RNA-Seq in Human Health and Disease
edited by
submission deadline 30 May 2024 | Viewed by 302 | Submission Open
Keywords: aging; bioinformatics; single-cell RNA-Seq; RNA-Seq
(This special issue belongs to the Section Molecular Informatics)
Brain Metastasis 2024
edited by
submission deadline 30 May 2024 | Viewed by 295 | Submission Open
Keywords: brain metastasis; brain microenvironment; pathology; circulating tumor cells; tumor-normal cell crosstalks; new biomarkers and therapies for brain metastasis; cerebral spinal fluid/liquid biopsy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Insights into Type 2 Diabetes and Its Complications
edited by
submission deadline 30 May 2024 | Viewed by 289 | Submission Open
Keywords: diabetes; metabolic defects; β -cell function; dietary intervention; physical exercise
(This special issue belongs to the Section Molecular Biology)
Gene Therapy in Neuropathy
edited by
submission deadline 30 May 2024 | Viewed by 286 | Submission Open
Keywords: gene therapy; adeno-associated viral vectors; lentiviral vectors; nanoparticles; antisense oligonucleotides; CRISPR Cas9; RNA; CNS; PNS
(This special issue belongs to the Section Molecular Genetics and Genomics)
Molecular Mechanisms of Musculoskeletal Involvement in Rare Diseases
edited by
submission deadline 30 May 2024 | Viewed by 276 | Submission Open
Keywords: rare diseases; molecular pathways; musculoskeletal system; bone involvement; joint degeneration
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular and Cellular Mechanisms of Gynecologic Malignancies, Benign Diseases 2.0
edited by
submission deadline 30 May 2024 | Viewed by 268 | Submission Open
Keywords: gynecologic malignancies; endometrial cancer; ovarian cancer; cervical cancer; uterine cancer; chemotherapy; target therapy; tumor marker; benign gynecologic diseases; endometriosis; polycystic ovary syndrome
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Advanced Glycoproteomics Research
edited by
submission deadline 30 May 2024 | Viewed by 262 | Submission Open
Keywords: glycosylation; glycoproteomics; site-specific glycan structures; glycan function; biochemical validation
(This special issue belongs to the Section Biochemistry)
Molecular and Electrophysiological Modulation in Cardiac Arrhythmias
edited by
submission deadline 30 May 2024 | Viewed by 261 | Submission Open
Keywords: arrhythmias; cardiac electrophysiology; molecular biology; ion channels; intracellular regulation; intracellular calcium dynamics; trafficking; post-translational modifications; structural alterations; gene expression; animal models; basic; translational and clinical science
(This special issue belongs to the Section Molecular Biology)
Molecular Mechanisms in Dry Eye Disease: Effects on Pathogenesis, Treatment and Ocular Surgery
edited by
submission deadline 30 May 2024 | Viewed by 255 | Submission Open
Keywords: dry eye disease; molecular mechanisms pathophysiology; pathogenesis; treatment
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Osteoarthritis Biomarkers, Diagnosis and Treatments
edited by
submission deadline 30 May 2024 | Viewed by 252 | Submission Open
Keywords: osteoarthritis; degenerative joint disease; biomarkers; diagnosis; treatments
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Role of Primary Cell Line Models in Evolutionary Molecular Physiology
edited by
submission deadline 30 May 2024 | Viewed by 251 | Submission Open
Keywords: cell physiology; fibroblasts; comparative biology; evolution; physiological ecology; vertebrates; primary cell line
(This special issue belongs to the Section Molecular Biology)
Cytokine Signaling in Development, Homeostasis and Disease
edited by
submission deadline 30 May 2024 | Viewed by 251 | Submission Open
Keywords: cytokine signaling; development; homeostasis; disease
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Plant Bioactive Compounds: Antioxidant, Anti-inflammatory and Anticancer Effects submission deadline 30 May 2024 | Viewed by 216 | Submission Open
Keywords: anticancer; antioxidant; anti-inflammatory; bioactive compounds; chemical biology; molecular biology; metabolic diseases; nutrition.
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Role of Steroids and Triterpenoids in Plant Growth, Development and Stress Response 2.0
edited by
submission deadline 30 May 2024 | Viewed by 214 | Submission Open
Keywords: biosynthesis; chemical defense; plant growth and development; steroids; sterols; stress response; triterpenoids
(This special issue belongs to the Section Molecular Plant Sciences)
Research Advances in Whole-Genome/Exome Sequencing (WGS/WES) and Next-Generation Sequencing
edited by
submission deadline 30 May 2024 | Viewed by 209 | Submission Open
Keywords: short/long-read sequencing; whole-exome sequencing; whole-genome sequencing; bioinformatics; variant classification models; translational medicine
(This special issue belongs to the Section Molecular Genetics and Genomics)
The Dynamics of Redox Metabolism in Plants submission deadline 30 May 2024 | Viewed by 206 | Submission Open
Keywords: plant metabolism; plant stress; post-translational modifications; reactive oxygen/nitrogen/sulfur species; redox regulation; signaling
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Advances in Blood–Brain Barrier, Blood–Cerebrospinal Fluid Barrier and Cerebrospinal Fluid–Brain Barriers submission deadline 30 May 2024 | Viewed by 201 | Submission Open
Keywords: blood– brain barrier (BBB); blood– cerebrospinal fluid (CSF) barrier (BCSFB); CSF– brain barriers (CSFBB); brain homeostasis; neuroscience; depression; multiple sclerosis; stroke
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Natural-Derived Nanocarriers as Delivery Systems for Biomolecules
edited by
submission deadline 30 May 2024 | Viewed by 194 | Submission Open
Keywords: natural nanocarriers; biomolecules; delivery systems; nanomedicine; human health; controlled release
(This special issue belongs to the Section Molecular Biology)
Model Organisms in Plant Science: Metal Transport in Tomato
edited by
submission deadline 30 May 2024 | Viewed by 185 | Submission Open
Keywords: metal; uptake; translocation; sequestration; transmembrane transport
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Computational Modelling in the Context of Safe and Sustainability-by-Design Strategy
edited by Alicja Mikołajczyk
submission deadline 30 May 2024 | Viewed by 183 | Submission Open
Keywords: molecular informatics; molecular computational modelling; materials modeling; molecular study; chemoinformatic design
(This special issue belongs to the Section Molecular Informatics)
Advances in Molecular Research of Diabetic Cardiomyopathy submission deadline 30 May 2024 | Viewed by 179 | Submission Open
Keywords: diabetic cardiomyopathy; apoptosis; diabetes; myocardial fibrosis; stem cells; inflammation; therapeutic approaches
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Circadian Biology in Human Health and Disease
edited by Flore Sinturel
submission deadline 30 May 2024 | Viewed by 174 | Submission Open
Keywords: circadian rhythms; metabolism; misalignment; synchronization; molecular clock; internal body clocks; sleep– wake cycle
(This special issue belongs to the Section Molecular Biology)
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