Global Expert Views on Aortic Valve Repair and Replacement
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiovascular Medicine".
Deadline for manuscript submissions: 30 November 2024 | Viewed by 1459
Special Issue Editor
Special Issue Information
Dear Colleagues,
The treatment of aortic valve pathologies has undergone important changes in recent years. Open cardiac surgery has been giving way to less aggressive techniques, including transcatheter or surgeries with a minimally invasive approach and with the intention of preserving the aortic valve in cases of valve regurgitation. These new techniques have managed to improve the clinical results of patients and reduce the risk of complications. All of these modern techniques require prior in-depth research that includes several imaging techniques, such as transesophageal echocardiography, multidetector cardiac tomography or cardiac magnetic resonance. The intention of this Special Issue is to showcase state-of-the-art techniques for aortic valve repair and replacement as well as the imaging techniques required for the correct planning of these procedures.
Dr. Jose Alberto De Agustín
Guest Editor
Manuscript Submission Information
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Keywords
- aortic valve pathologies
- minimally invasive approach
- aortic valve repair
- aortic valve replacement
- imaging techniques
Planned Papers
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Title: Aortic stenosis and the evolution of cardiac damage after transcatheter aortic valve replacement
Authors: Fabián Islas; Patrick O'neill; Pilar Jimenez-Quevedo; Luis Nombela-Franco; Sandra Gil-Abizanda; Patricia Mahía; María Rivadeneira; Eduardo Pozo; Andreina Carbone; Carmen Olmos
Affiliation: Instituto Cardiovascular Hospital Clinico San Carlos, Madrid, Spain
Abstract: Background/Objectives: Severe aortic stenosis (AS) is the most frequent valvular heart disease. Models for stratifying cardiac damage associated with aortic stenosis have been developed to predict outcomes following valve replacement. However, evidence regarding morphological and functional evolution and potential changes in the degree of cardiac damage is limited. We aim to provide information on the evolution of cardiac morphology and function of patients undergoing transcatheter aortic valve replacement (TAVR) classified using a cardiac damage staging system.
Methods: 496 patients were included in the analysis and were classified into four stages based on the extent of cardiac damage as follows: Stage 0, no cardiac damage: left ventricle global longitudinal strain (LV-GLS) < -17%; right ventricular-arterial coupling (RVAc) ≥ 0.35,) and absence of significant mitral regurgitation (MR). Stage 1, left-sided subclinical damage: LV-GLS ≥ -17%. Stage 2, left-sided damage: significant MR. Stage 3, right-sided damage: RVAc < 0.35.
Results: The mean age was 82.1±5.9 years and 53.0% were female. 24.5% of patients met the criteria for Stage 0, Stage 1 included 42.8%, Stage 2 included 16.5%, and Stage 3 comprised 16.2% of patients. Mortality was 8.4% for stage 0, 17.4% for stage 1, 25.6% for stage 2 and 28.6% for stage 3 patients (p= 0.004). Diabetes mellitus (DM) (p= 0.047) and chronic kidney disease (CKD) (p= 0.024) were the only clinical predictors of no change or worsening in the stage of cardiac damage. Regarding echocardiographic variables, concomitant tricuspid and mitral regurgitation 2 were significantly associated with no change or worsening (p
