Meeting the Challenge of Metabolomics Analysis by Using Multidimensional Gas Chromatography with Mass Spectrometry
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Metabolomic Profiling Technology".
Deadline for manuscript submissions: 31 October 2024 | Viewed by 5190
Special Issue Editors
Interests: multidimensional chromatography; GC×GC; metabolomics; phytochemistry; trace analysis of food contaminants and additives; microextraction techniques; chiral analysis
Interests: MDGC; GC×GC; foods and flavour analysis; environmental analysis; natural products analysis; drugs and pesticides analysis; prep-scale GC
Special Issue Information
Dear Colleagues,
Over the preceding two decades, multidimensional gas chromatography (MDGC) and its incarnation, comprehensive two-dimensional gas chromatography (GC×GC), have emerged as powerful bioanalytical tools for the study of metabolomics in many branches of life sciences. The hyphenation of GC×GC to mass spectrometry (MS) has further developed into a “super-resolution” technique that provides improved separation, detection, and identification of complex metabolomes. Notably, the utilization of multiple separation dimensions and the informing power of MS, especially high-resolution MS, have significantly expanded the coverage of detectable metabolites in biological matrices of living systems compared with GC−MS methods. In this Special Issue, we invite authors to disseminate their findings on the recent developments and applicability of MDGC and GC×GC−MS in advancing metabolomics studies. Submissions are welcome in the form of original research and review articles. We look forward to your valuable contributions.
Dr. Yong Foo Wong
Prof. Dr. Philip J. Marriott
Guest Editors
Manuscript Submission Information
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Keywords
- GC×GC
- MDGC
- metabolites
- high-resolution mass spectrometry
- metabolite profiling
- metabolite fingerprinting
- biomarker
- plant secondary compounds
- disease diagnosis