Structural Analysis and Biological Evaluation of Compounds from Fungi—2nd Edition

Dear Colleagues,

In recent years, increasing attention has been paid to the study of edible mushrooms that demonstrate medicinal functions. Mushrooms, such as Ganoderma sichuanense and Lentinula edodes, have been applied in clinical settings. However, although active compounds from mushrooms play a role in certain well-known signaling pathways involved in diseases, their mechanisms of action and target cells/molecules remain unclear.

The goal of this research topic is to identify compounds purified from mushrooms, explore their pharmacological properties, and clarify their mechanism of action and targets. Submitted manuscripts should adhere to the following requirements and scope:

1. The active compounds studied must be purified from mushrooms and subjected to explicit structural analysis. These compounds include, but are not limited to, polysaccharides, alkaloids, flavonoids, and various monomers. Please note that these compounds must have identified chemical structures.

2. The purified and structurally appraised compounds from mushrooms must demonstrate their pharmacological effects, which include, but are not limited to, immune-regulatory, anti-inflammatory, anti-neurodegenerative, anti-oxidative, and anti-tumor properties. Data obtained from in vitro experiments must be confirmed in animal models or preferably in clinical trials.

3. The study must clarify the mechanisms of action of the active compounds with a clear delineation of their targets, such as cells and cytokines associated with pharmacological properties.

Prof. Dr. Di Wang
Dr. Jia Song
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• fungi
• natural products
• structure analysis
• pharmacological properties
• mechanism
• disease

• Structural Analysis and Biological Evaluation of Compounds from Fungi in Molecules (12 articles)