Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
4.7
3.5
Journals
Processes
Special Issues
Advances and Prospects in Organic Synthesis
share announcement

Advances and Prospects in Organic Synthesis

A special issue of Processes (ISSN 2227-9717). This special issue belongs to the section "Chemical Processes and Systems".

Deadline for manuscript submissions: 30 November 2024 | Viewed by 378

Special Issue Editors

Dr. Vanessa Nascimento

E-Mail Website
Guest Editor
Adjunct Professor, SupraSelen Laboratory, Department of Organic Chemistry, Chemistry Institute, Fluminense Federal University, Niteroi 24020-150, RJ, Brazil
Interests: organic synthesis; organochalcogens; pillararene; supramolecular chemistry; sustainable synthesis
Dr. Luana Da Silva Magalhães Forezi

E-Mail Website
Guest Editor
Adjunct Professor, Applied Organic Synthesis Laboratory, Department of Organic Chemistry, Chemistry Institute, Fluminense Federal University, Niteroi 24020-141, RJ, Brazil
Interests: organic synthesis; photocatalysis; heterogeneous catalysis; solar cell
Special Issues, Collections and Topics in MDPI journals
Dr. Carolina Guimarães De Souza Lima

E-Mail Website
Guest Editor
Adjunct Professor, Research Group in Sustainable Organic Chemistry, Department of Organic Chemistry, Chemistry Institute, Fluminense Federal University, Niteroi 24020-141, RJ, Brazil
Interests: sustainable chemistry; organic synthesis; heterogeneous catalysis; pyrolysis; biomass upgrading; waste feedstocks

Special Issue Information

Dear Colleagues,

Organic synthesis is the process of designing and creating organic compounds through chemical reactions. In this context, advances in organic synthesis have played a crucial role in the development of various fields, including pharmaceuticals, materials science, and agriculture. There are several reports of novel technologies and strategies applied in such processes, and harnessing this knowledge could have a significant impact. These advances not only ensure a sustainable future by promoting resource efficiency and securing energy sources but also offer more effective therapeutic options.

In this context, the objective of this Special Issue is to provide a forum for the publication of original research and review articles focusing on the development, advancement, and utilization of organic compounds as major players in science advancement. This Special Issue will highlight the advances in organic synthesis with the potential to generate value for society.

Prospective focuses include, but are not limited to, the following:

  • The design and synthesis of biologically active compounds;
  • The investigation of new synthetic methodologies;
  • Process optimization for the synthesis of organic compounds;
  • Biomass-derived molecules as feedstocks in organic synthesis.

Dr. Vanessa Nascimento
Dr. Luana Da Silva Magalhães Forezi
Dr. Carolina Guimarães De Souza Lima
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Processes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • organic synthesis
  • synthetic methodology
  • bioactive compounds
  • multicomponent reactions
  • catalysis
  • green chemistry
  • sustainable chemistry
  • biomass upgrading

Published Papers (1 paper)

Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

12 pages, 483 KiB  
Article
Sodium Hypochlorite Pentahydrate as a Chlorinating Reagent: Application to the Tandem Conversion of β,γ-Unsaturated Carboxylic Acids to α,β-Unsaturated Lactones
by Michio Iwaoka, Reo Shimada, Masaki Kuroda, Takehito Ikeda and Eduardo E. Alberto
Processes 2024, 12(6), 1102; https://doi.org/10.3390/pr12061102 - 27 May 2024
Viewed by 131
Abstract
Sodium hypochlorite pentahydrate (NaClO·5H2O, 1) has recently been employed in organic synthesis as an oxidant for alcohols, sulfides, glycols, etc. In most of these reactions, however, reagent 1 functions just as a simple oxidant, and the variations of the reactions [...] Read more.
Sodium hypochlorite pentahydrate (NaClO·5H2O, 1) has recently been employed in organic synthesis as an oxidant for alcohols, sulfides, glycols, etc. In most of these reactions, however, reagent 1 functions just as a simple oxidant, and the variations of the reactions have not been well explored. In this study, we report another useful and fascinating reaction, in which reagent 1 functions as a green chlorinating reagent toward β,γ-unsaturated carboxylic acid (2). When substrate 2 was stirred at room temperature with 1 (2 eq) in acetonitrile for 1 h, α,β-unsaturated lactone (3) was obtained in moderate yields (up to 62%). The same reaction proceeded in various organic and aqueous solvents as well. When excess reagent 1 was employed, lactone 3 was further oxidized to the corresponding epoxide (4) for some cases. The conversion is initiated by electrophilic attack of HOCl to the C=C bond of 2 to generate a chloronium ion intermediate, which is cyclized to β-chlorolactone (5) and then 3 through the elimination of HCl. The usefulness of 1 as a chlorinating reagent was further demonstrated in the electrophilic substitution of activated aromatic compounds. Full article
(This article belongs to the Special Issue Advances and Prospects in Organic Synthesis)
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-1
Back to TopTop