Journal of Clinical Medicine

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Dear Colleagues,

On behalf of the Journal of Clinical Medicine’s Editorial team, We are delighted to present the Second Edition of the Special Issue “Diagnosis, Treatment, and Prevention of Glaucoma” (https://www.mdpi.com/journal/jcm/special_issues/X3WCT9P600).

Glaucoma is the second leading cause of blindness worldwide. It has been estimated that more than 70 million people are affected by the disease, with 8 million affected by bilateral blindness. Glaucoma is completely asymptomatic until the very advanced stages, and primary prevention is not feasible. Therefore, early diagnosis and early treatment are fundamental in preventing blindness.

Recent advances in technology have improved the diagnosis, prevention, and treatment of glaucoma. Optical coherence tomography development, a structure–function approach, and minimally invasive glaucoma surgery devices are just a few examples of these advances.

This Special Issue is focused on all aspects related to the diagnosis, treatment, and prevention of glaucoma. Authors are welcome to submit original, high-quality articles to contribute to the discussion in this field of research.

Dr. Manuele Michelessi
Dr. Gloria Roberti
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Related Special Issue

Published Papers (1 paper)

Research

12 pages, 1988 KiB

Open AccessFeature PaperArticle

The Clinical Efficacy of Different Relaxation Exercises on Intraocular Pressure Reduction: A Meta-Analysis

by Bing-Qi Wu, Hou-Ting Kuo, Alan Y. Hsu, Chun-Ju Lin, Chun-Ting Lai and Yi-Yu Tsai

J. Clin. Med. 2024, 13(9), 2591; https://doi.org/10.3390/jcm13092591 - 28 Apr 2024

Viewed by 415

Abstract

Objective: The aim of this study was to synthesize the available evidence on the clinical efficacy of different relaxation exercises on intraocular pressure (IOP) reduction. Methods: A systemic search of PubMed, Embase, Cochrane CENTRAL, and Web of Science was undertaken from the earliest record to 10 April 2024. Peer-reviewed studies that reported on healthy individuals and glaucoma patients engaging in relaxation exercises for at least three weeks were included. The primary outcome was changes in IOP levels from baseline, before the commencement of relaxation exercises, to post-exercise. Our statistical analysis employed a random-effects model, with effect sizes reported using Hedges’ g. Results: Twelve studies were included, totaling 764 eyes (mean participant age ranging from 21.07 to 69.50 years). Relaxation exercises significantly reduced IOP, with Hedges’ g being −1.276 (95% CI: −1.674 to −0.879) and I² = 84.4%. Separate subgroup analyses showed that breathing exercises (Hedges’ g = −0.860, p < 0.0001), mindfulness-based stress reduction (MBSR) (Hedges’ g = −1.79, p < 0.0001), and ocular exercises (Hedges’ g = −0.974, p < 0.0001) were associated with reduced IOP levels. The reduction in IOP following the relaxation exercises was found to be associated with baseline IOP either greater than (Hedges’ g = −1.473, p < 0.0001) or less than 21 mmHg (Hedges’ g = −1.22, p < 0.0001). Furthermore, this effect persisted with follow-up durations of less than (Hedges’ g = −1.161, p < 0.0001) and more than one month (Hedges’ g = −1.324, p < 0.0001). Conclusions: The current meta-analysis indicates that relaxation exercises can significantly reduce IOP levels. Relaxation exercises are a potential class of novel treatments for glaucoma patients that deserve further evaluation. Full article

(This article belongs to the Special Issue Diagnosis, Treatment, and Prevention of Glaucoma: Second Edition)

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